This section features links to a wide range of clinical resources on equivalent doses and conversions for opioids, benzodiazepines, antidepressants, antipsychotics, corticosteroids and more. When clonidine and beta blockers are taken together and clonidine is to be stopped, it is recommended that the beta blocker be withdrawn first, and then clonidine can be tapered over 2 - 4 days. OR. The most recent beta-blocker to enter the U.S. marketplace is nebivolol (Bystolic, Forest) (TABLE 2), approved by the FDA for the treatment of hypertension; in Europe, it is registered for use in mild-to-moderate, uncomplicated hypertension and mild-to-moderate heart failure and has been approved for hypertension outside Europe as well. Beta blockers equivalent dosing. The conversion comes in handy when a patient with atrial fibrillation has been rate controlled after a bolus of diltiazem and is on a diltiazem drip, but now needs conversion to an oral formulation. Pharmacy and Therapeutics Committee-approved Therapeutic Interchanges ... Alfuzosin and tamsulosin are therapeutically equivalent for the treatment of BPH and are the preferred ... Metoprolol is the preferred cardioselective beta blocker. 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts Based on recommended initial starting and target doses of these 2 beta-blockers in the various clinical trials CIBIS II, US Carvedilol Studies,12 and COPERNICUS, and the Clinical Pharmacy Practice Guidelines for HF patients developed by Singapore Ministry of Health, a 5:1 dose conversion (eg, carvedilol 12.5 mg BD to bisoprolol 5 mg OM). 6 … Hospital Pharmacist's Letter includes:. The Rx Files: Beta Blockers (BBs) Supplementary Tables Table 1 Contraindications and Precautions Contraindications • Sick sinus syndrome or 2nd/3rd degree AV block • Cardiogenic shock • Uncompensated CHF • Reactive airway disease (asthma,COPD,emphysema) Precautions • Severe hypotension (SBP<100 mm or HR <60) • Peripheral vascular disease - exacerbated especially by stable. Always consult your physician or pharmacist before taking medications concurrently. Atenolol is available for continuation of outpatient therapy. 12 issues every year, with brief articles about new meds and hot topics; 300+ CE courses, including the popular CE-in-the-Letter; Quick reference drug comparison charts Pharmacist's Letter Canada includes:. 6 Then check once or twice yearly, and when patient condition or medications change. Atenolol hasn't been shown to improve outcomes in hypertension, heart failure, or post-MI.. Use this as an opportunity to get patients on a better beta-blocker. Combogesic acetaminophen/ibuprofen An OTC combination analgesic for pain and fever in adults. Kynmobi apomorphine A quick-acting dopamine agonist for "off" episodes in Parkinson's disease Think of this as a good thing. Document contraindication(s) to beta-blocker. 1,6,8,37 If SCr increased, check again in 2 to 3 weeks, and again in 3 to 4 weeks. Document created: 08/11. carvedilol 12.5mg BID acebutolol 100mg BID metoprolol 50mg BID propranolol 40mg BID atenolol 50mg daily metoprolol SR 100mg daily propranolol LA (ER) 80mg daily - FDA daily max is 640mg bisoprolol 5mg daily nadolol 80mg daily - FDA daily max is 320 Prescribe* and document beta-blocker therapy of either carvedilol sustained release metoprolol succinate, or bisoprolol for patients ≥18 years with HF who have a current or prior LVEF < 40%. The recent atenolol shortage will renew debate about which beta-blocker to choose and how to switch.. Welcome to the equivalent dose and drug conversions / transfers / switching section of the website for physicians and pharmacists.